MEPE_HUMAN Q9NQ76
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UniProt:Q9NQ76
Recommended name：Matrix extracellular phosphoglycoprotein
EC number：
Alternative names：(Osteoblast/osteocyte factor 45) (OF45) (Osteoregulin)
Cleaved into：
GeneID：56955
Gene names (primary )：MEPE
Gene names (synonym )：
Gene names (ORF )：
Length：525
Mass：58419
Sequence：MRVFCVGLLLFSVTWAAPTFQPQTEKTKQSCVEEQRQEEKNKDNIGFHHLGKRINQELSSKENIVQERKKDLSLSEASENKGSSKSQNYFTNRQRLNKEYSISNKENTHNGLRMSIYPKSTGNKGFEDGDDAISKLHDQEEYGAALIRNNMQHIMGPVTAIKLLGEENKENTPRNVLNIIPASMNYAKAHSKDKKKPQRDSQAQKSPVKSKSTHRIQHNIDYLKHLSKVKKIPSDFEGSGYTDLQERGDNDISPFSGDGQPFKDIPGKGEATGPDLEGKDIQTGFAGPSEAESTHLDTKKPGYNEIPEREENGGNTIGTRDETAKEADAVDVSLVEGSNDIMGSTNFKELPGREGNRVDAGSQNAHQGKVEFHYPPAPSKEKRKEGSSDAAESTNYNEIPKNGKGSTRKGVDHSNRNQATLNEKQRFPSKGKSQGLPIPSRGLDNEIKNEMDSFNGPSHENIITHGRKYHYVPHRQNNSTRNKGMPQGKGSWGRQPHSNRRFSSRRRDDSSESSDSGSSSESDGD
Tissue specificity：Expressed by osteoblasts (PubMed:10945470, PubMed:11414762, PubMed:15108058). Expressed by stem cells in dental pulp (PubMed:15153459). Expressed by mesenchymal cells in dental papilla and dental pulp (PubMed:18547474, PubMed:22341070). Expressed in teeth, specifically in decidious dentin (PubMed:20581062). Expressed in ondotoblasts (PubMed:12489176). Expressed in salivary glands (PubMed:15329369). Secreted from oncogenic hypophosphatemic tumors (PubMed:11414762). {ECO:0000269|PubMed:10945470, ECO:0000269|PubMed:11414762, ECO:0000269|PubMed:12489176, ECO:0000269|PubMed:15108058, ECO:0000269|PubMed:15153459, ECO:0000269|PubMed:15329369, ECO:0000269|PubMed:18547474, ECO:0000269|PubMed:20581062, ECO:0000269|PubMed:22341070}.
Induction：
Developmental stage：
Protein families：PF07175/osteoregulin family